| Diffuse esophageal spasm | |
|---|---|
| Classification and external resources | |
| ICD-9 | 530.5 |
| DiseasesDB | 32060 |
| MedlinePlus | 000289 |
| eMedicine | med/743 |
| MeSH | D015155 |
Diffuse esophageal spasm (DES) is a condition in which uncoordinated contractions of the esophagus occur. It is thought to result from motility disorders of the esophagus. These spasms do not propel food effectively to the stomach. It can cause dysphagia, regurgitation and chest pain.
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Several drugs, including nitroglycerin and calcium channel blockers are used to treat this condition. Botulinum toxin, which inhibits acetylcholine release from nerve endings, may also be used in the treatment of DES by injections above the lower esophageal sphincter (although effects are temporary). Additionally, endoscopic balloon dilation has also been shown to improve symptoms of DES in small studies.[1]
It has been reported that very cold or hot beverages can trigger an esophageal spasm. Contrary, rapid swallowing of a liquid often provides immediate relief.
The condition is sometimes referred to as corkscrew esophagus, due to a characteristic appearance of the esophagus as a corkscrew on barium swallow x-rays.